Adult Leukemia

Table of Contents

Foreword
Preface

1. What Leukemia Is
     Understanding blood
     How leukemia begins
     How leukemia is diagnosed
     Kinds of adult leukemia
     Acute leukemias
     Chronic leukemias
     Other chronic lymphocytic leukemias
     Preleukemic conditions
     What leukemia is not

2. Signs and Symptoms
     Bringing concerns to your doctor
     Acute leukemias
     Chronic leukemias
     Hairy cell leukemia (HCL)

3. Diagnosis
     Diagnosis by blood work
     Who to see for testing
     Questions for a first visit
     Comprehensive blood testing
     Hearing the diagnosis
     Emotional responses to diagnosis

4. Tests and Procedures
     General information
     Specific tests

5. Subtype, Staging, and Prognosis
     Blood tests yield subtype and staging information
     Acute leukemias
     Chronic leukemias
     Hairy cell leukemia

6. Risks and Causes
     Who is at risk for leukemia
     Causal information
     Viral links to leukemia
     Speculative causes of leukemia
     Prevention and reducing risk

7. Treatment Options
     The range of treatment theories
     Standard therapies
     Chemotherapy
     Rescue drugs
     Biological therapies
     Choosing the best treatment option
     What to expect during treatment
     Treatment protocols
     Preparation
     Scheduling
     Administering therapies

8. Treatments for Individual Leukemias
     Treatment protocols
     Acute leukemias
     Chronic leukemias
     Adult T-cell leukemia (ATL)
     Prolymphocytic leukemia (PLL)
     Hairy cell leukemia (HCL)
     Splenic lymphoma with villous lymphocytes (SLVL)

9. Transplantation
     Bone marrow transplant basics
     Types of bone marrow transplants
     Considerations for patients and families
     How transplants are done
     After treatment
     Long-term effects
     Becoming a donor

10. Clinical Trials and Beyond
     Who should learn about clinical trials?
     What are clinical trials?
     Why participate in clinical trials?
     Guinea pig?
     Placebos
     How clinical trials are run
     Where to go for clinical trials
     Finding trials for leukemia
     Why research trials on your own?
     Getting admitted to a trial
     Once you are accepted
     Payment
     Future treatment directions
     Research in biological anticancer substances
     Research in chemotherapy

11. Communicating with Your Medical Team
     Establishing a relationship with your doctor
     Talking with your doctor
     Medical case managers
     Second opinions
     Communicating with the hospital staff

12. Side Effects of Treatment
     General observations
     Why do side effects arise?
     A word about prednisone
     Side effects of treatment

13. Stress and the Immune System
     What is stress?
     Responses to stress
     The effect of stress on the immune system
     What can we do?
     Stress reduction techniques
     Stress medications

14. Getting Support
     Specific needs
     Communicate these details
     Typical reactions
     How to communicate about needs
     Sources of support
     Loved ones
     Good friends
     Support groups
     Coworkers
     Individual and family counseling
     Organizations that focus on help
     Challenging moments

15. Insurance and Finances
     Health insurance
     Financial issues
     Disability income
     Employment issues
     Record-keeping
     Traveling for care

16. After Treatment
     Leaving the world of treatment
     Moving on
     Emotional responses
     Social and professional after-effects
     Lingering symptoms and side effects
     Late effects and complications

17. Recurrence
     Recurrence defined
     Causes for recurrence
     What to look for
     When am I safe from fears of relapse?
     Treatment options
     Transformations
     Emotional responses
     Mobilizing for treatment again
     Adjusting to treatment again
     What family and friends can do
     What the patient can do

18. If All Treatments Have Failed
     Setting new goals
     Emotional concerns
     Physical aspects of dying
     Can we make dying easier?
     Planning your own memorial ceremony

19. Researching Your Leukemia
     Why researching helps
     What you'll need to begin
     Ways to find information
     Getting started
     Research papers from medical journals
     How to obtain medical textbooks
     Finding clinical trials
     How to find support groups
     How to verify drug information
     Verifying your chemotherapy dose
     How to interpret test results
     How to assess unproven remedies
     Other unique web resources
     What next?

A. Resources
B. Normal Blood and Marrow Test Values
C. Body Surface Area in Square Meters
D. FAB Staging of Acute Leukemia
E. Genetic Classification of the Lymphocytic Leukemias
F. Progression of Cell Development
G. Leukemia Drugs
Notes
Glossary
Index